解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract:BACKGROUND:The current study assessed the feasibility of a mentored home-based vegetable gardening intervention and examined changes in health-related outcomes among breast cancer survivors (BCS). METHODS:BCS were randomized to either a year-long vegetable gardening intervention to begin immediately or a wait-list con...
journal_title:Cancer
pub_type: 杂志文章,随机对照试验
doi:10.1002/cncr.31559
更新日期:2018-08-01 00:00:00
abstract:BACKGROUND:To the authors' knowledge, relatively little is known regarding the interaction of risk factors for hepatocellular carcinoma (HCC) with age, sex, and liver disorder status. METHODS:The authors followed 504,646 Korean patients aged 40 to 80 years who underwent routine health checkups between 2002 and 2003 un...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.31406
更新日期:2018-07-01 00:00:00
abstract:BACKGROUND:Evidence of racial disparities in the receipt of postmastectomy breast reconstruction is well documented. The objective of this study was to describe trends in racial disparities overall and by reconstructive technique. METHODS:The American College of Surgeons National Surgical Quality Improvement Program d...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.31395
更新日期:2018-07-01 00:00:00
abstract:BACKGROUND:This study explores whether externalizing religious and spiritual beliefs is associated with advanced-stage colon cancer at initial oncology presentation and whether this association is stronger for blacks than for whites. METHODS:Patients who had newly diagnosed, invasive colon cancer were recruited at 9 s...
journal_title:Cancer
pub_type: 杂志文章,多中心研究
doi:10.1002/cncr.31351
更新日期:2018-06-15 00:00:00
abstract:BACKGROUND:Oral tongue cancer incidence has increased among whites in the United States; however, the cause remains unknown. If an infectious agent is implicated, then elevated risk would be expected among immunosuppressed individuals. METHODS:By using population-based registry linkage information from the US Transpla...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.31359
更新日期:2018-06-15 00:00:00
abstract:BACKGROUND:False-positive cancer screening results may affect a patient's willingness to obtain future screening. METHODS:The authors conducted logistic regression analysis of 450,484 person-years of electronic medical records (2006-2015) in 92,405 individuals aged 50 to 75 years. Exposures were false-positive breast,...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.31271
更新日期:2018-06-01 00:00:00
abstract:BACKGROUND:Posttransplant lymphoproliferative disorder (PTLD) is a life-threatening complication of solid organ transplantation. Histologic heterogeneity and a lack of treatment standards have made evaluating clinical outcomes in specific patient populations difficult. This systematic literature review investigated the...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.31339
更新日期:2018-06-01 00:00:00
abstract:BACKGROUND:The current study was performed to describe patient characteristics, treatment patterns, survival, health care resource use (HRU), and costs among older women in the United States with advanced (American Joint Committee on Cancer stage III/IV) triple-negative breast cancer (TNBC) in the Surveillance, Epidemi...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.31299
更新日期:2018-05-15 00:00:00
abstract:BACKGROUND:Biomarker-guided clinical trials are increasingly common in metastatic urothelial carcinoma (mUC), yet patients for whom contemporary tumor tissue is not available are not eligible. Technological advancements in sequencing have made cell-free circulating DNA (cfDNA) next-generation sequencing (NGS) readily a...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.31314
更新日期:2018-05-15 00:00:00
abstract:BACKGROUND:The assessment of pancreatic ductal adenocarcinoma (PDAC) response to therapy remains challenging. The objective of this study was to investigate whether changes in the tumor/parenchyma interface are associated with response. METHODS:Computed tomography (CT) scans before and after therapy were reviewed in 4...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.31251
更新日期:2018-04-15 00:00:00
abstract:BACKGROUND:Although outcomes for patients with squamous cell carcinoma of the anus (SCCA) have improved, the gains in benefit may not be shared uniformly among patients of disparate socioeconomic status. In the current study, the authors investigated whether area-based median household income (MHI) is predictive of sur...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.31186
更新日期:2018-04-15 00:00:00
abstract:BACKGROUND:Outcomes have improved significantly in multiple myeloma (MM), but racial disparities in health care access and survival exist. A comprehensive analysis exploring MM care and racial disparities is warranted. METHODS:Patients with MM from 1991 to 2010 in the Surveillance, Epidemiology, and End Results-Medica...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.31237
更新日期:2018-04-15 00:00:00
abstract:BACKGROUND:Gene expression profiling (GEP) has been rapidly adopted for early breast cancer and can aid in chemotherapy decision making. Study results regarding racial disparities in testing are conflicting, and may reflect different care settings. To the authors' knowledge, data regarding the influence of provider fac...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.31222
更新日期:2018-04-15 00:00:00
abstract:BACKGROUND:Tyrosine kinase inhibitors (TKIs) have improved the outcome of patients with gastrointestinal stromal tumors (GISTs), but most patients eventually develop resistance and progress. Dasatinib is a potent inhibitor of BCR-ABL, KIT, and SRC family kinases as well as imatinib-resistant cells. In GISTs, response e...
journal_title:Cancer
pub_type: 杂志文章,多中心研究
doi:10.1002/cncr.31234
更新日期:2018-04-01 00:00:00
abstract:BACKGROUND:A phase 1 trial was used to evaluate a combination of cisplatin, gemcitabine, and escalating doses of veliparib in patients with untreated advanced pancreatic ductal adenocarcinoma (PDAC) in 2 cohorts: a germline BRCA1/2-mutated (BRCA+) cohort and a wild-type BRCA (BRCA-) cohort. The aims were to determine t...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.31218
更新日期:2018-04-01 00:00:00
abstract:BACKGROUND:To the authors' knowledge, there are few studies to date regarding colorectal cancer (CRC) beliefs, knowledge, and screening among multiple Asian American populations, who are reported to have lower CRC screening rates compared with white individuals. The current study was performed to assess knowledge and b...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.31216
更新日期:2018-04-01 00:00:00
abstract:BACKGROUND:The objective of this study was to describe characteristics at diagnosis and outcomes of adults with soft tissue sarcoma. METHODS:The authors conducted a retrospective multicenter study of 12,262 patients who were treated between January 1980 and 31 December 2013 in French Sarcoma Group centers and enrolled...
journal_title:Cancer
pub_type: 杂志文章,多中心研究
doi:10.1002/cncr.31176
更新日期:2018-03-15 00:00:00
abstract:BACKGROUND:Chemotherapy-induced nausea and vomiting remain common, distressing side effects of chemotherapy. It has been reported that acupressure prevents chemotherapy-induced nausea in adults, but it has not been well studied in children. METHODS:In this multicenter, prospective, randomized, single-blind, sham-contr...
journal_title:Cancer
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1002/cncr.31198
更新日期:2018-03-15 00:00:00
abstract:BACKGROUND:Poor enrollment of adolescents and young adults (AYAs) (ages 15-39 years) onto cancer clinical trials (CCTs) may contribute to inferior survival gains compared with children. In this study, the authors assessed whether differences in CCT availability would explain lower CCT enrollment for early AYAs (eAYAs) ...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.31127
更新日期:2018-03-01 00:00:00
abstract:BACKGROUND:Sedentary behaviors are associated with poor health outcomes in the general population, but their clinical impact on adult survivors of childhood acute lymphoblastic leukemia (ALL) has not been characterized to date. In the current study, we described the prevalence of sedentary behaviors in survivors of ALL...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.31162
更新日期:2018-03-01 00:00:00
abstract:BACKGROUND:Genomic testing is increasingly performed in oncology, but concerns remain regarding the clinician's ability to interpret results. In the current study, the authors sought to determine the agreement between physicians and genomic annotators from the Precision Oncology Decision Support (PODS) team at The Univ...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.31112
更新日期:2018-03-01 00:00:00
abstract:BACKGROUND:In the current national debate regarding private insurance versus Medicaid expansion, understanding how insurance is associated with racial disparities in prostate cancer (CaP) outcomes has broad policy implications. In the current study, the authors examined the association between insurance status, race, a...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.31106
更新日期:2018-02-15 00:00:00
abstract:BACKGROUND:Children with average-risk acute lymphoblastic leukemia (AR-ALL) face many challenges that can adversely affect their quality of life (QOL). However, to the authors' knowledge, patterns and predictors of QOL impairment during therapy have not been well characterized to date. METHODS:Patients with AR-ALL who...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.31085
更新日期:2018-02-01 00:00:00
abstract:BACKGROUND:Patients with prostate cancer receiving androgen deprivation therapy (ADT) are at risk of sleep disturbance; however, to the authors' knowledge, the mechanisms by which ADT may affect sleep are not well understood. The current study compared objective and subjective sleep disturbance in ADT recipients and co...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.31024
更新日期:2018-02-01 00:00:00
abstract:BACKGROUND:There is increasing evidence that radiation therapy (RT) can be omitted for select older patients who are compliant with hormonal blockade, but there is no recent claim-based analysis for determining patterns of care and guiding possible treatment recommendations. METHODS:Medicare beneficiaries who were 65 ...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.30989
更新日期:2018-02-01 00:00:00
abstract:BACKGROUND:There is no clear consensus between pediatric and adult providers about the treatment of adolescents and young adults (AYAs) with Hodgkin lymphoma (HL). METHODS:Failure-free survival (FFS) and overall survival (OS) were compared between 114 patients ages 17 to 21 years with HL who were treated on the Easter...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.30979
更新日期:2018-01-01 00:00:00
abstract:BACKGROUND:Early-phase trials in patients with recurrent neuroblastoma historically used an objective "response" of measureable disease (Response Evaluation Criteria In Solid Tumors [RECIST], without bone/bone marrow assessment) to select agents for further study. Historical cohorts may be small and potentially biased;...
journal_title:Cancer
pub_type: 杂志文章,meta分析,评审
doi:10.1002/cncr.30934
更新日期:2017-12-15 00:00:00
abstract:BACKGROUND:Overall, cervical cancer survival in the United States has been reported to be among the highest in the world, despite slight decreases over the last decade. Objective of the current study was to describe cervical cancer survival trends among US women and examine differences by race and stage. METHODS:This ...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.30906
更新日期:2017-12-15 00:00:00
abstract:BACKGROUND:Stomach cancer was a leading cause of cancer-related deaths early in the 20th century and has steadily declined over the last century in the United States. Although incidence and death rates are now low, stomach cancer remains an important cause of morbidity and mortality in black, Asian and Pacific Islander...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.30881
更新日期:2017-12-15 00:00:00
abstract:BACKGROUND:Patients with advanced cancer often experience frequent and prolonged hospitalizations; however, the factors associated with greater health care utilization have not been described. We sought to investigate the relation between patients' physical and psychological symptom burden and health care utilization. ...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.30912
更新日期:2017-12-01 00:00:00
abstract:BACKGROUND:Patient safety is a critical concern in clinical oncology, but the ability to measure adverse events (AEs) across cancer care is limited by a narrow focus on treatment-related toxicities. The objective of this study was to assess the nature and extent of AEs among cancer patients across inpatient and outpati...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.30916
更新日期:2017-12-01 00:00:00
abstract:BACKGROUND:Filanesib (ARRY-520) is a highly selective inhibitor of kinesin spindle protein, which has demonstrated preclinical antimyeloma activity. METHODS:This open-label Phase 1/2 study determined the maximum tolerated dose of Filanesib administered on Days 1 and 2 of 14-Day Cycles in patients with multiple myeloma...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.30892
更新日期:2017-12-01 00:00:00
abstract:BACKGROUND:Screening over many years is required to optimize reductions in colorectal cancer (CRC) mortality. However, no prior trials have compared strategies for obtaining long-term adherence. METHODS:Systems of Support to Increase Colorectal Cancer Screening and Follow-Up was implemented in an integrated health car...
journal_title:Cancer
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1002/cncr.30908
更新日期:2017-11-15 00:00:00
abstract:BACKGROUND:Children receiving immunosuppressive treatment for cancer are at high risk for invasive pneumococcal disease. The 13-valent pneumococcal conjugate vaccine (PCV13) can prevent pneumococcal disease in healthy children; however, there is an absence of literature regarding the benefit of PCV13 in immunocompromis...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.30764
更新日期:2017-11-01 00:00:00
abstract:BACKGROUND:During the last decade, an inverse stage migration has been observed in radical prostatectomy series at tertiary centers. However, it remains unclear whether similar trends can also be observed in solely robotic practices, including nonreferral centers. The aim of this study was to investigate the clinical a...
journal_title:Cancer
pub_type: 杂志文章,多中心研究
doi:10.1002/cncr.30874
更新日期:2017-11-01 00:00:00
abstract:BACKGROUND:Little is known about the size and characteristics of the decision-support networks of women newly diagnosed with breast cancer and whether their involvement improves breast cancer treatment decisions. METHODS:A population-based sample of patients newly diagnosed with breast cancer in 2014 and 2015, as repo...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.30848
更新日期:2017-10-15 00:00:00
abstract:BACKGROUND:Testicular cancer survivors (TCS) have an increased risk of treatment-related cardiovascular disease (CVD), which may limit their overall survival. We evaluated the effects of high-intensity aerobic interval training (HIIT) on traditional and novel CVD risk factors and surrogate markers of mortality in a pop...
journal_title:Cancer
pub_type: 杂志文章,随机对照试验
doi:10.1002/cncr.30859
更新日期:2017-10-15 00:00:00
abstract:BACKGROUND:The difficulties adolescents and young adults (AYAs) encounter during a cancer experience may result in a reduction in or absence of empowerment. The aims of the current study were to assess levels of empowerment and associated (demographic, clinical, or psychological) factors and examine the association bet...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.30827
更新日期:2017-10-15 00:00:00
abstract:BACKGROUND:Severe fatigue is a common and distressing symptom affecting approximately one in four survivors of breast cancer. The current study examined the efficacy of Internet-based cognitive behavioral therapy (ICBT) for severe fatigue in survivors of breast cancer compared with care as usual (CAU). METHODS:The aut...
journal_title:Cancer
pub_type: 杂志文章,随机对照试验
doi:10.1002/cncr.30815
更新日期:2017-10-01 00:00:00
abstract:BACKGROUND:Programmed death 1 (PD-1) signaling in the tumor microenvironment dampens immune responses to cancer, and blocking this axis induces antitumor effects in several malignancies. Clinical studies of PD-1 blockade are only now being initiated in pediatric patients, and little is known regarding programmed death-...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.30724
更新日期:2017-10-01 00:00:00